1st ETN School: CaSR: Molecular and clinical aspects
1st ETN School: “CaSR: Molecular and clinical aspects” | Lead: R.V. Thakker (UOXF) | 12-14.12.2016 | |
Objectives: Molecular and clinical aspects of CaSR-dependent signalling; Good Scientific Practice: Standards, requirements and professional conduct. | Open to external students | ECT: 2.5 | |
Course: CaSR and beyond: (responsible R.V. Thakker): • How it all began: short history of the CaSR (E. Brown, D. Riccardi) • GPCR-signalling from biophysics to intracellular networks (F. Bruggeman, H. Bräuner–Osborne); • structure, function, and signalling through the CaSR (L. Pugliese, G. Breitwieser);• Ligand-biased signalling and conditional efficacy of the CaSR (D. Ward, A. Conigrave). • CaSR-dependent genetic disorders (F.M. Hannan). | |||
Workshop (WS): From diagnosis to therapy: (responsible M.L. Brandi). The role of the CaSR • in developmental tumourigenesis (C. de Torres), • diabetes, (F. Hannan); • genetic disorders of mineral metabolism and congenital bone diseases (M.L. Brandi); • neuronal diseases (A. Dinnyes) • Endocrine diseases caused by CaSR mutations (R.V. Thakker). Aetiology, clinical manifestations and treatment options will be presented. | |||
WS: Ethics in Scientific Research: (responsible S. Baumgartner-Parzer): • principles and rules of Good Scientific Practice; • general aspects of hypothesis generation, study protocols; data management and documentation; • publications, authorship criteria and sequence, • scientific misconducts, conflicts of interest, etc | |||
WS: Quality Management in research: (responsible A. Hollo-Tas) • Closing event of an e-Learning course that will have examined the possibilities offered by applying Quality Management principles to this ETN. | |||
1st ETN School and 1st Annual Meeting
"The 1st ETN School was held in the Somerville College and was a great opportunity for the new ESRs from the CaSR Biomedicine Training Network to get to know each other and all the members of this consortium. During this week there was not only time for the ESRs to absorb all the knowledge and advice given by their principal investigators and the advisory board members, but also to strengthen the relationship among each other.
During the 1st Annual Meeting (the last two days of this week) there was the chance for the ESRs to present their plans and any initial data that they may have. There was lively discussion being held as well as good input from all the attendants. In my personal opinion there seems to be a bright future ahead for the research of the calcium-sensing receptor. "
Eliana Goncalves Alves (ESRs' Representative)
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